An Uncommon Case of Orbital Myofibroma in Adult: case report

Resumo

Introdução: O miofibroma foi descrito inicialmente por Williams Schrum em 1951 como fibrossarcoma congênito. É um tumor benigno incomum de células mesenquimais exibindo diferenciação miofibroblástica que ocorre principalmente na primeira década de vida. Relato do caso: Paciente do sexo masculino, 44 anos, apresentado ao ambulatório de neurocirurgia com histórico de diplopia e abaulamento do globo ocular esquerdo, acuidade visual normal e nenhuma outra anormalidade foi encontrada no exame oftalmológico. A ressonância magnética da cabeça foi realizada com contraste intravenoso, apresentando lesão bem definida medindo 3,3 × 2,4 cm em sequência ponderada em T2 na região orbitária esquerda e intracraniana envolvendo o globo ocular esquerdo e estendendo-se até o seio etmoidal, osso frontal, músculo reto medial e nervo óptico. Posteriormente, o paciente foi submetido à craniotomia fronto-orbitária esquerda para ressecção tumoral. Foi realizada uma orbitotomia da borda orbitária superior esquerda para a excisão tumoral. O estudo de microscopia e imuno-histoquímica é mais consistente com o diagnóstico de miofibroma/miopericitoma orbital. Discussão e Conclusão: Relatamos uma ocorrência rara de miofibroma adulto na região orbital. O paciente apresentou excelente recuperação pós-operatória e está em acompanhamento ambulatorial.

Palavras-chave

Palavras-chave: Miofibroma; Miofibromatose; Olho; Neoplasia; Adulto

Abstract

Introduction: Myofibroma was initially described by Williams Schrum in 1951 as Congenital Fibrosarcoma. This is an uncommon benign tumor of mesenchymal cells exhibiting myofibroblastic differentiation that occurs mainly in the first decade of life. Case Presentation: A 44-year-old male patient presented to the neurosurgery clinics with a history of diplopia and bulging of his left eyeball, his visual acuity was normal, and no other abnormalities were found on ophthalmological examination. The Magnetic Resonance Imaging of the head was performed with intravenous contrast. It showed a well-defined lesion measuring 3.3 × 2.4 cm in T2-weighted sequence in the left orbital and intracranial region involving the left eyeball and extending to the ethmoid sinus, frontal bone, medial rectus muscle and optic nerve. Subsequently, the patient underwent a left fronto-orbital craniotomy for tumor resection. The microscopy and immunohistochemistry study are most consistent with the diagnosis of an orbital myofibroma/myopericytoma. Discussion and Conclusion: We reported a rare occurrence of adult myofibroma in the orbital region. The patient had excellent postoperative recovery and is under ambulatory follow-up.

Keywords

Keywords: Myofibroma; Myofibromatosis; Eye; Neoplasms; Adult

References

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An Uncommon Case of Orbital Myofibroma in Adult: case report

Um Caso Incomum de Miofibroma de Órbita em Adulto: relato de caso

Resumo

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Abstract

Keywords

References

JBNC Brazilian Journal of Neurosurgery

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