ORIGINAL
Introdução: O diagnóstico da patologia aneurismática está ficando cada vez mais prevalente na população geral, em especial com o aumento da expectativa de vida. A dilatação das artérias cerebrais em paciente com idade avançada tende a estar cada vez mais presente na rotina do neurocirurgião. Dessa forma, a investigação de aneurismas cerebrais em pacientes idosos torna-se relevante no manejo clínico-cirúrgico dessas pessoas. Objetivo: Estabelecer relação entre idade e propensão à doença aneurismática, assim como traçar perfil clínico-epidemiológico nessa faixa etária. Métodos: Estudo observacional descritivo, de indivíduos com idade maior ou igual a 70 anos, com diagnóstico de aneurisma cerebral, submetidos ao tratamento endovascular em serviço de neurocirurgia endovascular do Hospital Santa Isabel, Blumenau, Santa Catarina, no período de 2005 a 2023. Resultados: O sexo feminino foi o mais acometido (75,81%), o aneurisma sacular foi o mais prevalente (95,81%), e a dimensão pequena (69,76%). O tratamento endovascular foi o método optado nessa gama de pacientes, onde a terapia com a utilização de coils foi a mais prevalente (66,97%). Conclusão: O quadro aneurismático em idosos apresentou características gerais similares ao paciente adulto. Contudo, o processo de envelhecimento manifestou-se em certas nuances na apresentação clínica como, por exemplo, nas comorbidades associadas. Esse tópico requer maior investigação em literatura, especialmente em pacientes com idade superior a 80 anos, onde o menor número de indivíduos torna desafiante a análise científica.
Introduction: Aneurysmal pathology is becoming increasingly prevalent in the general population, especially as life expectancy increases. Dilation of cerebral arteries in elderly patients tends to be increasingly present in neurosurgeons’ routine. Therefore, the investigation of cerebral aneurysms in elderly patients is relevant to their clinical and surgical management. Objective: to establish a relationship between age and propensity to aneurysmal disease, as well as to draw up a clinical-epidemiological profile in this age group. Methods: Descriptive observational study of individuals aged 70 or older diagnosed with cerebral aneurysm who underwent endovascular treatment at the Endovascular Neurosurgery Service of the Santa Isabel Hospital between 2005 and 2023. Results: Females were the most affected (75.81%), saccular aneurysms were the most prevalent (95.81%), and their size was often small (69.76%). Endovascular treatment was the method of choice for this group of patients, with coil therapy being the most prevalent (66.97%). Conclusion: Aneurysms in the elderly had similar general characteristics to those in adult patients; however, the aging process manifested itself in certain nuances in clinical presentation, such as associated comorbidities. This topic requires further investigation in the literature, especially in patients over the age of 80, where the smaller number of individuals makes scientific analysis challenging.
1. Toth G, Cerejo R. Intracranial aneurysms: review of current science and management. Vasc Med. 2018;23(3):276-88. http://dx.doi. org/10.1177/1358863X18754693. PMid:29848228.
2. Jersey AM, Foster DM. Cerebral Aneurysm. 2018. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507902/. Accessed: 11/21/2023.
3. Wiebers DO, Whisnant JP, Huston J 3rd, et al. Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment. Lancet. 2003;362(9378):103-10. http://dx.doi. org/10.1016/S0140-6736(03)13860-3. PMid:12867109.
4. Smith RR, Zubkov YN, Tarassoli Y. The history of aneurysm surgery. In: Smith RR, Zubkov YN, Tarassoli Y, editors. Cerebral Aneurysms. New York, Springer; 1994. p. 1-9. http://dx.doi.org/10.1007/978-1- 4613-9532-4_1.
5. Hishikawa T, Date I. Unruptured cerebral aneurysms in elderly patients. Neurol Med Chir (Tokyo). 2017;57(6):247-52. http://dx.doi. org/10.2176/nmc.ra.2016-0286. PMid:28428448.
6. Iwamoto H, Kiyohara Y, Fujishima M, et al. Prevalence of intracranial saccular aneurysms in a Japanese community based on a consecutive autopsy series during a 30-year observation period: the Hisayama study. Stroke. 1999;30(7):1390-5. http://dx.doi.org/10.1161/01.STR.30.7.1390. PMid:10390312.
7. Vlak MH, Algra A, Brandenburg R, Rinkel GJ. Prevalence of unruptured intracranial aneurysms, with emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta-analysis. Lancet Neurol. 2011;10(7):626-36. http://dx.doi.org/10.1016/ S1474-4422(11)70109-0. PMid:21641282.
8. Byoun HS, Huh W, Oh CW, Bang JS, Hwang G, Kwon OK. Natural history of unruptured intracranial aneurysms: a retrospective single center analysis. J Korean Neurosurg Soc. 2016;59(1):11-6. http://dx.doi. org/10.3340/jkns.2016.59.1.11. PMid:26885281.
9. Lanzino G, Kassell NF, Germanson TP, et al. Age and outcome after aneurysmal subarachnoid hemorrhage: why do older patients fare worse? J Neurosurg. 1996;85(3):410-8. http://dx.doi.org/10.3171/ jns.1996.85.3.0410. PMid:8751625.
10. Sedat J, Dib M, Rasendrarijao D, Fontaine D, Lonjon M, Paquis P. Ruptured intracranial aneurysms in the elderly: epidemiology, diagnosis, and management. Neurocrit Care. 2005;2(2):119-23. http://dx.doi. org/10.1385/NCC:2:2:119. PMid:16159053.
11. Inagawa T, Yamamoto M, Kamiya K, Ogasawara H. Management of elderly patients with aneurysmal subarachnoid hemorrhage. J Neurosurg. 1988;69(3):332-9. http://dx.doi.org/10.3171/jns.1988.69.3.0332. PMid:3404228.
12. Sakaki S, Ohta S, Ohue S, Kohno K, Matsuoka K. Outcome in elderly patients with ruptured intracranial aneurysm. Clin Neurol Neurosurg. 1989;91(1):21-7. http://dx.doi.org/10.1016/S0303-8467(89)80004-6. PMid:2538277.
1 MS, Medical student, Medical School, Regional University of Blumenau, Blumenau, state of Santa Catarina, Brazil.
2 MD, PhD, Endovascular Neurosurgery, Medical School, Regional University of Blumenau, Santa Isabel Hospital, Blumenau, Santa Catarina, Brazil.
Received Nov 21, 2023
Accepted Nov 27, 2023